GOLD NANOPARTICLES IN BIOMEDICAL APPLICATIONS

Biomedical Applications of Gold Nanoparticles

Gold nanoparticles display unique properties which allow them to influence a number of different biochemical processes. Interestingly, these effects are dependent on the particle surface chemistry which varies considerably based on the particle size. In addition, unlike most of other nanomaterials, gold nanoparticles do not trigger the formation of pro-inflammatory multiprotein complexes, known...

Functionalized Gold Nanoparticles and Their Biomedical Applications

Metal nanoparticles are being extensively used in various biomedical applications due to their small size to volume ratio and extensive thermal stability. Gold nanoparticles (GNPs) are an obvious choice due to their amenability of synthesis and functionalization, less toxicity and ease of detection. The present review focuses on various methods of functionalization of GNPs and their application...

Electrochemical genosensors for biomedical applications based on gold nanoparticles.

Two gold nanoparticles-based genomagnetic sensors designs for detection of DNA hybridization are described. Both assays are based on a magnetically induced direct electrochemical detection of gold tags on magnetic graphite-epoxy composite electrodes. The first design is a two strands assay format that consists of the hybridization between a capture DNA strand which is linked with paramagnetic b...

Superparamagnetic Iron oxide-Gold Core-Shell Nanoparticles for Biomedical Applications

Iron oxide nanoparticles are used for contrast enhancement in magnetic resonance imaging (MRI). We have prepared gold-coated iron oxide nanoparticles that show no change in their superparamagnetic behavior as a consequence of coating. Their potential use as MRI contrast agents was investigated by monitoring their T2 relaxation time with concentration. Cytotoxicity of these nanoparticles was als...

Gold Nanoshells in Biomedical Applications